Christina Applegate Reveals MS Misdiagnosis: “I Am Back At Square One”

Deadline - Oct 20, 2026

Christina Applegate, who was diagnosed with multiple sclerosis back in 2021 and has become a leading advocate for people coping with the disease, revealed shocking news Tuesday: She was misdiagnosed and does not in fact have MS. In an emotional episode of MeSsy, the podcast she hosts with Jamie Lynn Sigler as, in Applegate’s description, […]

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